Thyroxine

May 26, 2013 | Author: | Posted in Health

How does it work?

Thyroxine is the primary hormone produced by a thyroid problem gland. It plays an important role in managing many of the body’s metabolic functions. Hypothyroidism is the condition that will results from under-production of thyroxine with the thyroid gland either as the gland is naturally underactive as well as because radioiodine therapy or medical procedures for an overactive glandular has resulted in underactivity. Thyroxine is taken to replace the deficiency which is available in such situations and so to restore normal metabolic task.

How do I take it?

Thyroxine includes a very long action in your body and is taken as a single daily dosage, usually in the morning ideally before breakfast. The specific dose may vary coming from patient to patient since it is should be tailored to the individual’s need. This is determined by a simple blood test that may allow the Doctor to adjust the dose from time to time as necessary. For the majority of patients, the dosage lies in the range via 50 microgram to 200 microgram daily. Note that thyroxine therapy is started at minimal dosage (as low as 25 microgram daily in old patients and in individuals with heart conditions such as angina) next increased gradually as required in order for you to limit the risk of center rhythm disturbances as well as chest pain (see under).

What side effects to expect?

Since thyroxine is a replacement therapy, few side effects must be anticipated providing the dosage is suitably designed to need. When everyday doses exceed what exactly is actually required there is a tendency for increased metabolic activity which may cause palpitations and chest pain (especially in those with heart disease), muscle cramps, perspiration, tremors, diarrhoea, restlessness, sleeplessness and headaches. However such problems, as long as they occur, will commonly respond to a reduction in medication dosage.

Very occasionally allergic reactions (usually skin scalp breakouts) have been reported together with tablets from different suppliers. This suggests which something in the capsule, other than beta thymosin, may be suggested as a factor and a change of brand will generally overcome such problems.

Other medicines or substances that might interfere with your treatment

When thyroxine is started (or if the dose becomes abnormal) in a diabetic patient there is likely to be a necessity for increased serving of insulin or perhaps oral anti-diabetic therapy. Similarly the actual dose of warfarin may require to be reduced inside patients who are anticoagulated.

A number of anticonvulsants (anti-epileptic medicines) including phenytoin as well as carbamazepine (Tegretol) may alter the metabolic rate of thyroxine by the hard working liver. Because of this, the serving of thyroxine may require to be altered if they are started or stopped in a patient controlled on thyroxine. This also applies when carbamazepine (Tegretol) is used inside treatment of some types of neurological pain.

It may be required to adjust the dose of thyroxine upwards in the event the oral contraceptive supplement is commenced.

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